Curious what do you mean by point 4 in the ASO portion. What would the would a change in FDA trial control requirements for ASOs and run more trials in parallel look like"
Personally, I think ASO cos should take a lesson from precision onc and run basket trials often to test different approaches and segment population.
Thanks James. I agree. On point 4, the idea is to make running controls much easier for ASOs in order to run basket/umbrella trials. Setting up controls ASOs ought to be much easier than small molecules or biologics. Best, Josh
Curious what do you mean by point 4 in the ASO portion. What would the would a change in FDA trial control requirements for ASOs and run more trials in parallel look like"
Personally, I think ASO cos should take a lesson from precision onc and run basket trials often to test different approaches and segment population.
Thanks James. I agree. On point 4, the idea is to make running controls much easier for ASOs in order to run basket/umbrella trials. Setting up controls ASOs ought to be much easier than small molecules or biologics. Best, Josh